By Steve Wachow, M. D., M. P. H., Ph. D., F. A. B., F. C.
A slimming pill called orlistat (Xenical®) is one of the most commonly used weight-loss pills for weight management. Its effects last from six months to a year and are generally well-tolerated, but people with chronic weight management problems may experience gastrointestinal side effects. Orlistat is also used to help with weight loss.
Xenical (the active ingredient in Xenical®) is a lipase inhibitor, and it is often taken in conjunction with a low-calorie diet. It is also known as a "water pill," meaning it works by blocking fat absorption from the digestive system. When taken with a low-calorie diet, orlistat is usually taken at bedtime. Some people who take orlistat for weight loss may experience nausea, diarrhea, or stomach cramps. Orlistat has no known negative side effects, but it can cause unpleasant stomach ache and bloating. If you take orlistat for weight loss, your doctor will monitor you for these side effects and may adjust your dosage or suggest a different medication.
Xenical is usually taken once or twice daily. This type of pill has a longer duration of action and can be taken for up to six months, but you should not take this type of pill to prevent weight gain. The most common side effects of this drug include oily stool, gas, and diarrhea. These side effects are usually mild and go away on their own without taking a second dose. However, if these side effects persist or become bothersome, you should talk to your doctor.
Most people who take orlistat for weight loss will have an effect on their menstrual cycle and will not experience side effects. If you experience any changes in your menstrual cycle, you should talk to your doctor or nurse. However, if you experience bleeding problems during or after taking orlistat, check with your doctor or nurse. Your doctor will decide if you should continue to take orlistat, and if you should discontinue taking this drug.
The most common side effects of this drug are diarrhea, abdominal pain, flatulence, and nausea.
If you experience any of these side effects, talk to your doctor. Your doctor may also be able to tell you if these side effects are a result of other medications you take.
This article is for informational purposes only and does not constitute medical advice. Never take any medication without doctor’s advice or if you have any questions.
Bakker, K., Doreen, J., Rook, C., Bremel, J., Gershon, J., Stoddard, D., Loehrig, E., & Verma, E. (2019). Effect of orlistat on menstrual cycle and pregnancy outcomes in women with chronic weight management.
Updated 2022-2025
Orlistat has been shown to cause mild side effects in some individuals. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious effects, seek medical attention immediately.
Common side effects of orlistat use include:
More serious side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a serious adverse reaction–or allergic reaction–to this medication and require treatment right away.
Orlistat has been shown to affect the absorption of fat-soluble vitamins (vitamin A, D, E and K). This can prevent individuals taking this medication from receiving valuable nutrients from their food. Your doctor may recommend that you take a multivitamin and beta-carotene supplement along with this medication to ensure that you are receiving adequate nutrition from the food you eat.
As with all medication, inform your health care provider of any medical conditions you are currently managing. Let them know if you have or ever had kidney stones, diabetes, liver disease, gallbladder disease, thyroid disease, or an eating disorder (anorexia or bulimia). In addition, you should tell them if you have ever had an organ transplant, cholestasis (reduced or stopped bile flow), or malabsorption syndrome.
Tell your provider about any and all medication, prescription drugs, and supplements you are taking before starting treatment with orlistat. Orlistat can interact with substances in the body, causing potentially serious adverse reactions. Specifically, you should inform them of any immunosuppressant medication you are currently taking, such as cyclosporine. You should also let your provider know if you are currently taking blood thinners–like warfarin–or diabetes medication–like metformin.
In addition, let your doctor know if you are planning to become pregnant, are pregnant, or are currently breastfeeding before starting treatment with this medication.
paralysisAlternatively, you may choose to not take this medication if you have type 2 or 3 diabetes, or a history of gallbladder disease, thyroid disease, or vitamin B12 deficiency. Your doctor may then determine the appropriate amount of alcohol during treatment with orlistat.
If you experience any side effects, contact your doctor.
This medication can interact with:
This condition involves the wrong underlying cause, which can cause you to experience side effects or other adverse reactions. In addition, this medication can cause mild to moderate discomfort, including nausea, diarrhea, headaches, and dizziness. However, these symptoms may go away afteron taking treatment as your body adjusts to the medication.
For guidance on using this medication, a qualified healthcare provider should have knowledge of treatment options and any symptoms that may be required.
Xenical (orlistat) is an innovative weight loss medication that aids individuals in managing obesity by inhibiting the absorption of dietary fats in the intestine. Obesity is a significant health concern that increases the risk of various conditions, including heart disease, diabetes, and hypertension. Xenical offers a unique approach to weight management by preventing the breakdown and absorption of about 30% of the fat consumed in a meal, which is then excreted from the body. This reduction in fat absorption helps lower overall caloric intake, making it easier for individuals to lose weight and maintain a healthy lifestyle. When combined with a balanced diet and regular exercise, Xenical can significantly improve weight loss outcomes and reduce obesity-related health risks. It is a valuable tool for those struggling with weight management, providing support and efficacy in achieving long-term weight loss goals.
Benefits of Xenical:
Dosage:
Warnings and Precautions:
Usage Instructions:
Storage Information:
Common Side Effects:
Notes:
| Active Ingredient | Hydration | Effect on Metabolism |
|---|---|---|
| Orlistat | DHT | Reduces fat absorption |
| Acetylcholine | Tocumented | Increases blood flow |
| L-Arginine | ||
| Furosemide | Enhances blood flow |
Active ingredient:Orlistat.
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Alli is a top weight-loss brand in South Africa,...View MoreAlli is a top weight-loss brand in South Africa, offering a range of effective products. With trusted reviews and a commitment to quality, Alli helps individuals achieve their weight-loss goals safely and efficiently.View LessRead More
Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
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Product options Weight loss meal plan no active ingredients Xenical capsule no prescription How does the medication work?Orlistat works by blocking the absorption of about 30% of the fat in the body. This is due to its amino acid amino-tide, and it inhibits the lipase enzyme that breaks down this important hormone. This leads to an environment that is essential for the proper functioning of the body.
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